Will Aspirin prevent acute lung injury in critically ill patients? Dr. Kang

Vimmi Kang, DO

Article Review

The effect of aspirin in transfusion-related acute lung injury in critically ill patients

Source: Anesthesia. 20012 FEB 11

            This article looked to examine if aspirin would protect against transfusion related acute lung injury in critically ill patients. This article stemmed from the recent models that showed aspirin to be beneficial in improving outcomes in transfusion related injury in animals. This study was conducted as a post analysis of a case-control study. It looked at Transfusion-related acute lung injury cases compared with the control. Study consisted of 218 patients of which 66 used aspirin. Results showed that use of aspirin did not change the risk of transfusion related acute lung injury after transfusion of platelets or plasma.

In conclusion, aspirin did not decrease or protect against transfusion-related acute lung injury in critically ill patients.