Vik Belous,
DO
Article:
Malignant Hyperthermia in a patient with Graves’ disease
during subtotal thyroidectomy
Kozo Nishiyama, et al. Endocrine Journal. 2001, 48 (2),
227-232.
Summary:
In this article authors describe a case report of a patient
with Graves’ disease who developed malignant hyperthermia while undergoing a
subtotal thyroidectomy under general anesthesia. There are a few important take
home points from this reading. Patients in hypermetabolic state either
secondary to thyroid storm or malignant hyperthermia have overlapping signs,
which makes the distinction difficult especially in a patient under general
anesthesia. Nevertheless, anesthesia provider must remain vigilant about making
correct diagnosis. Muscle rigidity is not always a sure way to differentiate MH
and thyroid toxicity. Laboratory studies will help with making final diagnosis,
yet dantrolene therapy should be instituted as soon as possible. One should
keep in mind that there some reports suggesting a relationship between MH and
hyperthyroidism.
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